GC-MS Gas Chromatography Mass Spectrometry

Gas chromatography-mass spectrometry (GC-MS) is the preferred method for combining the qualities of gas chromatography and mass-spectrometry in order to identify samples.  The GC performs the separation while the MS identifies and can quanitate on the components.

Polyhedron Laboratories GS-MS testing is a method of choice for a number of contamination, odor and failure analysis applications.  These analyses include product identification, phthalates, Bis-Phenol A, polybrominated biphenyl ethers and residual monomers.  Polyhedron Laboratories GC-MS testing is also effective at identifying unknown mixtures of components.

Polyhedron Laboratories GS-MS test procedures are used extensively in the plastics and chemical industries.  Polyhedron Laboratories GS-MS methods are conducted according to the most stringent laboratory testing standards using the latest technical equipment and procedures.

There are two ways to conduct GC-MS analyses and they are by the headspace method and the direct solution injection method.  In the headspace method samples are heated in sealed containers and gas is withdrawn from the headspace above the solid or the solution. After injection into the GC-MS, the components are cryogenically trapped on the capillary column and then the temperature is ramped up.  The spectrum of each component is then searched with the NIST Mass Spectral library for identification of the components.

In the direct solution injection method the sample must be introduced in a very volatile solvent so that it passes through the column before any of the components of interest reach the mass spectrometer.  Here too the components are identified by the NIST Mass Spectral data base. 

Additionally each of the above methods can be run by acquiring all of the ions generated in the mass spectrometric (TIC) or by selective ion monitoring (SIM).  The latter method gives a higher sensitivity and is used for quanitation when looking for low levels of specific organic compounds